3-二甲氨基甲基-7-氮杂吲哚合成路线 (共 24 条)
反应条件
1: With acetic acid in water; N,N-dimethyl-formamide
T=110°C; 8 h;
2: With potassium carbonate in water; N,N-dimethyl-formamide
参考文献
Pierce, Larry T.; Cahill, Michael M.; McCarthy, Florence O.
Tetrahedron, 2011 , vol. 67, # 25 p. 4601 - 4611
反应条件
acetic acid in water; N,N-dimethyl-formamide
T=110°C; Inert atmosphere;
参考文献
Van Zandt, Michael C.; Doan, Brian; Sawicki, Diane R.; Sredy, Janet; Podjarny, Alberto D.
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 7 p. 2006 - 2008
参考文献
Robinson; Robinson
Journal of the American Chemical Society, 1956 , vol. 78, p. 1247,1249
反应条件
1: aqueous HCl
2: platinum; water; ethanol / Hydrogenation.Reagens 4:HCl
View Scheme
参考文献
ONO PHARMACEUTICAL CO., LTD.; Ohata, Akira; Nakatani, Shingo; Sugiyama, Tetsuya; Morimoto, Takashi
Patent: US2013/109699 A1, 2013 ;