反应条件
1: With N-ethyl-N,N-diisopropylamine; trichlorophosphate in 1,2-dichloro-ethane T=20°C; 13.5 h; 2: With ammonia in chloroform; water
参考文献
ARRAY BIOPHARMA INC.; GENENTECH, INC.; MITCHELL, Ian, S.; BLAKE, James, F.; XU, Rui; KALLAN, Nicholas, C.; XIAO, Dengming; SPENCER, Keith, Lee; BENCSIK, Josef, R.; LIANG, Jun; SAFINA, Brian; ZHANG, Birong; CHABOT, Christine; DO, Steven
Patent: WO2008/6040 A1, 2008 ;
Location in patent: Page/Page column 40; 95 ;
WO 2008/006040 A1