4-苯基-2-氮杂环丁酮合成路线 （共 52 条）
反应条件
Yield given. Multistep reaction;
参考文献
Journal of the Chemical Society, Chemical Communications, , # 9 p. 539 - 540
反应条件
in acetonitrile 21 h; Heating;
参考文献
Mattingly; Miller
Journal of Organic Chemistry, 1981 , vol. 46, # 8 p. 1557 - 1564
反应条件
1: 48 percent / KOH, Bu4NHSO4 / tetrahydrofuran / 20 °C 2: 70 percent / liq. NH3 / 336 h / 45 °C / sealed tube View Scheme
参考文献
Begley, Michael J.; Crombie, Leslie; Haigh, David; Jones, Raymond C. F.; Osborne, Steven; Webster, Richard A. B.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 17 p. 2027 - 2046
反应条件
1: 84 percent / KOH; Bu4NBr / tetrahydrofuran 2: 17 percent Turnov. / H2 View Scheme
参考文献
Achilles, Karin; Schirmeister, Tanja; Otto, Hans-Hartwig
Archiv der Pharmazie, 2000 , vol. 333, # 8 p. 243 - 253
反应条件
CAL-B (lipase B from Candida antarctica); water in isopropyl alcohol T=60°C; 24 h; Product distribution; Further Variations:ReagentsSolventsenzyme quantity;
参考文献
Park, Seongsoon; Forro, Enikoe; Grewal, Harjap; Fueloep, Ferenc; Kazlauskas, Romas J.
Advanced Synthesis and Catalysis, 2003 , vol. 345, # 8 p. 986 - 995
反应条件
water in various solvent(s) T=20°C; 24 h;
参考文献
Li, Xiang-Guo; Laehitie, Maria; Paeivioe, Mari; Kanerva, Liisa T.
Tetrahedron Asymmetry, 2007 , vol. 18, # 13 p. 1567 - 1573
反应条件
CAL-B (lipase B from Candida antarctica); water in isopropyl alcohol T=60°C; 24 h; Product distribution; Further Variations:ReagentsSolventsenzyme quantity;
参考文献
Advanced Synthesis and Catalysis, , vol. 348, # 7-8 p. 917 - 923
反应条件
water in various solvent(s) T=20°C; 24 h;
参考文献
Li, Xiang-Guo; Laehitie, Maria; Paeivioe, Mari; Kanerva, Liisa T.
Tetrahedron Asymmetry, 2007 , vol. 18, # 13 p. 1567 - 1573
反应条件
CAL-B (lipase B from Candida antarctica); water in isopropyl alcohol T=60°C; 24 h; Product distribution; Further Variations:ReagentsSolventsenzyme quantity;
参考文献
Advanced Synthesis and Catalysis, , vol. 348, # 7-8 p. 917 - 923
反应条件
water in various solvent(s) T=20°C; 24 h;
参考文献
Li, Xiang-Guo; Laehitie, Maria; Paeivioe, Mari; Kanerva, Liisa T.
Tetrahedron Asymmetry, 2007 , vol. 18, # 13 p. 1567 - 1573
