N-(N-叔丁氧羰基-N-甲基甘氨酰)-N-甲基甘氨酸合成路线 （共 4 条）
反应条件
1: With water; lithium hydroxide hydrate in tetrahydrofuran
2: With hydrogenchloride in water
pH=3;
参考文献
Vertex Pharmaceuticals Incorporated
Patent: US2012/309758 A1, 2012 ;
Location in patent: Page/Page column 66 ;
US 20120309758 A1
反应条件
1: DCC
2: aq. NaOH / methanol
View Scheme
参考文献
Bonora,G.M.; Toniolo,C.
Gazzetta Chimica Italiana, 1977 , vol. 107, p. 381 - 385
反应条件
sodium hydroxide in methanol
参考文献
Bonora,G.M.; Toniolo,C.
Gazzetta Chimica Italiana, 1977 , vol. 107, p. 381 - 385
反应条件
2: DCC
3: aq. NaOH / methanol
View Scheme
参考文献
Bonora,G.M.; Toniolo,C.
Gazzetta Chimica Italiana, 1977 , vol. 107, p. 381 - 385
