pyridine in dichloromethane
T=0 - 23°C; Inert atmosphere;
参考文献
Craig, Robert A.; O'Connor, Nicholas R.; Goldberg, Alexander F. G.; Stoltz, Brian M.
Chemistry - A European Journal, 2014 , vol. 20, # 16 p. 4806 - 4813
1: triethylamine; 4-(N,N-dimethlyamino)pyridine / dichloromethane / 0.8 h / 0 - 20 °C / |Inert atmosphere
2: zinc dibromide / dichloromethane / 0.17 h / 23 °C / |Inert atmosphere
3: magnesium / methanol / 0.5 h / 23 °C / |Inert atmosphere; |Sonication
View Scheme
参考文献
Craig, Robert A.; O'Connor, Nicholas R.; Goldberg, Alexander F. G.; Stoltz, Brian M.
Chemistry - A European Journal, 2014 , vol. 20, # 16 p. 4806 - 4813
1: (2R)-2-amino-2-phenyl-1-ethanol With sodium hydride in tetrahydrofuran; mineral oil
T=20°C; Inert atmosphere;
2: methyl iodide in tetrahydrofuran; mineral oil
T=20°C; 4 h; Inert atmosphereReflux;
参考文献
Airiau, Etienne; Spangenberg, Thomas; Girard, Nicolas; Schoenfelder, Angele; Salvadori, Jessica; Taddei, Maurizio; Mann, Andre
Chemistry - A European Journal, 2008 , vol. 14, # 35 p. 10938 - 10948