(S)-2-氨基-1-苯乙醇合成路线 （共 64 条）
反应条件
1: acetyl chloride / 24 h / 20 °C 2: 3.88 g / aqueous NH3 / methanol / 24 h / cooling View Scheme
参考文献
Tetrahedron, , vol. 62, # 49 p. 11402 - 11412
反应条件
1: 86 percent / HCO2H; Et3N; (R,R)-N-tosyl-1,2-diphenylethylenediamine / [Ru(cymene)Cl2]2 2: 27 percent / TFA / CH2Cl2 View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 11, # 16 p. 3257 - 3261
反应条件
trifluoroacetic acid in dichloromethane acidolysis;
参考文献
Kawamoto, Aparecida; Wills, Martin
Tetrahedron Asymmetry, 2000 , vol. 11, # 16 p. 3257 - 3261
反应条件
ammonia in methanol; water T=15 - 20°C; Title compound not separated from byproducts;
参考文献
Tetrahedron Asymmetry, , vol. 14, # 21 p. 3297 - 3300
反应条件
1: borane-THF; (S)-3,3-diphenyl-1-methyltetrahydro-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborol / tetrahydrofuran / 0.75 h / 65 °C 2: ammonium hydroxide / methanol; water / 20 °C View Scheme
参考文献
Organic Process Research and Development, , vol. 10, # 5 p. 893 - 898
反应条件
1: With dimethylsulfide borane complex; C10H18BNO in tetrahydrofuran T=0°C; Reflux; 2: With hydrogenchloride; water in tetrahydrofuran T=20°C; 5 h; optical yield given as percent eeenantioselective reaction;
参考文献
Synthesis, , # 2 art. no. P14610SS, p. 316 - 324
反应条件
1: 3.88 g / aqueous NH3 / methanol / 24 h / cooling View Scheme
参考文献
Tetrahedron, , vol. 62, # 49 p. 11402 - 11412
反应条件
1: With dimethylsulfide borane complex; C10H18BNO in tetrahydrofuran T=0°C; Reflux; 2: With hydrogenchloride; water in tetrahydrofuran T=20°C; 5 h; optical yield given as percent ee;
参考文献
Synthesis, , # 2 art. no. P14610SS, p. 316 - 324
反应条件
1: With dimethylsulfide borane complex; C10H18BNO in tetrahydrofuran T=0°C; Reflux; 2: With hydrogenchloride; water in tetrahydrofuran T=20°C; 5 h; optical yield given as percent ee;
参考文献
Synthesis, , # 2 art. no. P14610SS, p. 316 - 324
反应条件
1: With dimethylsulfide borane complex; C13H24BNO2 in tetrahydrofuran T=0°C; Reflux; 2: With hydrogenchloride; water in tetrahydrofuran T=20°C; 5 h; optical yield given as percent ee;
参考文献
Synthesis, , # 2 art. no. P14610SS, p. 316 - 324
