(S)-2-氨基-1-苯乙醇合成路线 （共 64 条）
反应条件
1: butan-1-ol / dibutyl ether / 116 h / 40 °C / lipase PS 2: 235 mg / KOH / methanol; H2O / 40 h / Heating View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 14 p. 1759 - 1762
反应条件
1: 2-methyl-butan-2-ol / 72 h / 40 °C / lipase PS 2: KOH / methanol; H2O / 40 h / Heating View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 14 p. 1759 - 1762
反应条件
potassium hydroxide in methanol; water 40 h; Heating; Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 14 p. 1759 - 1762
反应条件
sodium tetrahydroborate; (R)-Alpine-Borane®; cobalt(II) chloride 2.) methanol; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 50, # 17 p. 3237 - 3239
参考文献
Journal of the Chemical Society, , p. 2674,2680
Helvetica Chimica Acta, , vol. 18, p. 1190,1195
反应条件
sodium hydroxide; sodium hypobromide
参考文献
Chemistry and Industry (London, United Kingdom), , p. 527
反应条件
2: NaBrO; aq. NaOH solution View Scheme
参考文献
Chemistry and Industry (London, United Kingdom), , p. 527
参考文献
Helvetica Chimica Acta, , vol. 66, # 7 p. 2279 - 2284
反应条件
1: With potassium hydrogencarbonate in isopropanol acetate T=80°C; Substitution; 2 h; 2: With 4-(N,N-dimethlyamino)pyridine; TEA; p-toluenesulfonyl chloride in dichloromethane T=20°C; Cyclization; 40.6667 h; Further stages.;
参考文献
Schaus; Jacobsen
Organic letters, 2000 , vol. 2, # 7 p. 1001 - 1004
反应条件
ammonium acetate in methanol; water 5 h; Heating;
参考文献
Matsuoka, Yuki; Ishida, Yasuhiro; Sasaki, Daisuke; Saigo, Kazuhiko
Tetrahedron, 2006 , vol. 62, # 34 p. 8199 - 8206
