N-(3-甲氧基苯基)-2,2-二甲基丙酰胺合成路线 （共 24 条）
反应条件
pyridine; 4-(N,N-dimethlyamino)pyridine in dichloromethane T=0°C; 1 h;
参考文献
Ooi, Takashi; Takahashi, Makoto; Yamada, Masao; Tayama, Eiji; Omoto, Kiyoyuki; Maruoka, Keiji
Journal of the American Chemical Society, 2004 , vol. 126, # 4 p. 1150 - 1160
反应条件
potassium carbonate in acetone T=40°C; 24 h;
参考文献
Dai, Wei-Min; Cheung, Yuk King; Tang, Kit Wan; Choi, Pui Yiu; Chung, Suet Lam
Tetrahedron, 1995 , vol. 51, # 45 p. 12263 - 12276
反应条件
triethylamine in diethyl ether T=0 - 20°C; 0.025 h;
参考文献
WO2005/26158 A1, ;
Page/Page column 32 ;
WO 2005/026158 A1
反应条件
triethylamine in ethyl acetate T=60°C; Inert atmosphereSealed tube;
参考文献
Cai, Shangjun; Chen, Chao; Sun, Zelin; Xi, Chanjuan
Chemical Communications, 2013 , vol. 49, # 40 p. 4552 - 4554
反应条件
1: 76 percent / pyridine / tetrahydrofuran / 16.5 h / Ambient temperature 2: 93 percent / K2CO3 / acetone / 24 h / 40 °C View Scheme
参考文献
Tetrahedron, , vol. 51, # 45 p. 12263 - 12276
反应条件
1: 76 percent / pyridine / tetrahydrofuran / 16.5 h / Ambient temperature 2: 93 percent / K2CO3 / acetone / 24 h / 40 °C View Scheme
参考文献
Tetrahedron, , vol. 51, # 45 p. 12263 - 12276
反应条件
1: 89 percent / pyridine / tetrahydrofuran / 24 h / Ambient temperature 2: 93 percent / K2CO3 / acetone / 24 h / 40 °C View Scheme
参考文献
Tetrahedron, , vol. 51, # 45 p. 12263 - 12276
反应条件
1: 83 percent / tetrahydrofuran / 24 h / 80 °C 2: 93 percent / K2CO3 / acetone / 24 h / 40 °C View Scheme
参考文献
Tetrahedron, , vol. 51, # 45 p. 12263 - 12276
反应条件
1: 80 percent / n-BuLi / tetrahydrofuran / 3 h / 0 °C 2: 88 percent / 12N HCl / 1,2-dimethoxy-ethane / Heating View Scheme
参考文献
Hewawasam, Piyasena; Meanwell, Nicholas A.
Tetrahedron Letters, 1994 , vol. 35, # 40 p. 7303 - 7306
反应条件
1: sec-BuLi / tetrahydrofuran; hexane / 1.) 0 deg C, 2 h, 2.) 0 deg C, 1 h; r.t., 12 h 2: KHMDS / tetrahydrofuran; hexane; toluene / 1.) 0 deg C, 10 min, 2.) r.t., 2 h View Scheme
参考文献
Ubeda, J. Ignacio; Villacampa, Mercedes; Avendano, Carmen
Synthesis, 1998 , # 8 p. 1176 - 1180
