5-氨基-2-氯嘧啶合成路线

10320-42-02-氯-5-硝基嘧啶

56621-90-05-氨基-2-氯嘧啶

参考文献

Pathway Therapeutics Limited
Patent: US2011/9405 A1, 2011 ;
Location in patent: Page/Page column 56 ;

3264-10-62-羟基-5-硝基嘧啶

56621-90-05-氨基-2-氯嘧啶

参考文献

US2003/181465 A1, ;
US 20030181465 A1

56621-90-05-氨基-2-氯嘧啶

4983-28-22-氯-5-羟基嘧啶

参考文献

Jin, Hongxia; Randazzo, James; Zhang, Peng; Kador, Peter F.
Journal of Medicinal Chemistry, 2010 , vol. 53, # 3 p. 1117 - 1127

56621-90-05-氨基-2-氯嘧啶+

1711-07-5间氟苯甲酰氯

582323-10-2

参考文献

Amato, George; Roeloffs, Rosemarie; Rigdon, Greg C.; Antonio, Brett; Mersch, Theresa; McNaughton-Smith, Grant; Wickenden, Alan D.; Fritch, Paul; Suto, Mark J.
ACS Medicinal Chemistry Letters, 2011 , vol. 2, # 6 p. 481 - 484

56621-90-05-氨基-2-氯嘧啶+

76903-88-33,4-二氟苯甲酰氯

582323-16-8

参考文献

Amato, George; Roeloffs, Rosemarie; Rigdon, Greg C.; Antonio, Brett; Mersch, Theresa; McNaughton-Smith, Grant; Wickenden, Alan D.; Fritch, Paul; Suto, Mark J.
ACS Medicinal Chemistry Letters, 2011 , vol. 2, # 6 p. 481 - 484