1,4-双[(1H-咪唑-1-基)甲基]苯合成路线 （共 7 条）
反应条件
in methanol; water mixing of soln. of org.ligand in MeOH and soln. of M(OAc)2 in water, addn. of soln. of NaN3 in water, stirring (room temp., 10 min; pptn.); stirring (6 h), filtration, washing water, MeOH, ether), drying (vac.); elem. anal.;
参考文献
Synthesis and Reactivity in Inorganic and Metal-Organic Chemistry, , vol. 29, # 8 p. 1331 - 1338
反应条件
in methanol; water mixing of soln. of org.ligand in MeOH and soln. of M(OAc)2 in water, addn. of soln. of NaN3 in water, stirring (room temp., 10 min; pptn.); stirring (6 h), filtration, washing water, MeOH, ether), drying (vac.); elem. anal.;
参考文献
Synthesis and Reactivity in Inorganic and Metal-Organic Chemistry, , vol. 29, # 8 p. 1331 - 1338
反应条件
in methanol; water mixing of soln. of org.ligand in MeOH and soln. of M(OAc)2 in water, addn. of soln. of NaN3 in water, stirring (room temp., 10 min; pptn.); stirring (6 h), filtration, washing water, MeOH, ether), drying (vac.); elem. anal.;
参考文献
Synthesis and Reactivity in Inorganic and Metal-Organic Chemistry, , vol. 29, # 8 p. 1331 - 1338
反应条件
sodium hydride in N,N-dimethyl-formamide; mineral oil
T=20°C; 6 h;
参考文献
AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH; ZHANG, Yugen; LIU, Lihong
Patent: WO2012/50531 A1, 2012 ;
Location in patent: Page/Page column 18-20; 22 ;
反应条件
potassium hydroxide in isopropyl alcohol
参考文献
Shen, Xu-Jie; Chen, Hui-Lan; Yu, Fei; Zhang, You-Cai; Yang, Xiao-Hong; Li, Yi-Zhi
Tetrahedron Letters, 2004 , vol. 45, # 36 p. 6813 - 6817
反应条件
sodium hydroxide in dimethyl sulfoxide
参考文献
Haque, Rosenani A.; Ghdhayeb, Mohammed Z.; Salman, Abbas Washeel; Budagumpi, Srinivasa; Khadeer Ahamed, Mohamed B.; Abdul Majid, Amin M.S.
Inorganic Chemistry Communications, 2012 , vol. 22, p. 113 - 119
反应条件
1: 74 percent / NBS, AIBN / methyl formate / 14 h / Heating; Irradiation
2: methanol / 18 h / Heating
View Scheme
参考文献
Shen, Hao-Yu; Liao, Dai-Zheng; Jiang, Zong-Hui; Yan, Shi-Ping; Wang, Geng-Lin; Yao, Xin-Kan; Wang, Hong-Gen
Acta Chemica Scandinavica, 1999 , vol. 53, # 6 p. 387 - 390
