1-[(1R)-1-苯基乙基]-1H-咪唑-5-羧酸合成路线 （共 3 条）
反应条件
tetra(n-butyl)ammonium hydroxide in N,N-dimethyl-formamide T=120°C; 0.0833333 h;
参考文献
Eriksson, Jonas; Antoni, Gunnar; Langstroem, Bengt
Journal of Labelled Compounds and Radiopharmaceuticals, 2004 , vol. 47, # 11 p. 723 - 731
反应条件
lithium hydroxide hydrate in tetrahydrofuran; methanol
T=20°C;
参考文献
THE GENERAL HOSPITAL CORPORATION; ANNOVATION BIOPHARMA, LLC; RAINES, Douglas, E.; HUSAIN, Syed Shaukat; RANDLE, John, C.R.
Patent: WO2013/106717 A1, 2013 ;
Location in patent: Paragraph 00196 ;
反应条件
1: With sodium hydroxide; water
T=100°C; 1 h; Heating / reflux;
2: With acetic acid in water
参考文献
GE HEALTHCARE LIMITED
Patent: WO2007/144725 A2, 2007 ;
Location in patent: Page/Page column 15-16 ;
WO 2007/144725 A2
