2-溴-5-甲氧基苯甲酰氯合成路线 （共 16 条）
反应条件
1: H2O / 1 h 2: 16.1 g / BH3 / tetrahydrofuran / 5 h View Scheme
参考文献
Nielsen, Simon F.; Larsen, Mogens; Boesen, Thomas; Schonning, Kristian; Kromann, Hasse
Journal of Medicinal Chemistry, 2005 , vol. 48, # 7 p. 2667 - 2677
反应条件
1.1: H2O / 1 h
2.1: 16.1 g / BH3 / tetrahydrofuran / 5 h
3.1: Pd(OAc)2; 1,3-bis(diphenylphosphino)propane; aq. K2CO3 / dimethylformamide / 80 °C
3.2: 80 percent / aq. HCl / dimethylformamide / 1 h
View Scheme
参考文献
Nielsen, Simon F.; Larsen, Mogens; Boesen, Thomas; Schonning, Kristian; Kromann, Hasse
Journal of Medicinal Chemistry, 2005 , vol. 48, # 7 p. 2667 - 2677
反应条件
ammonium hydroxide in dichloromethane
参考文献
American Cyanamid Co.
Patent: US5519133 A1, 1996 ;
参考文献
Tang, Xiubo; Zhang, Dongheng; Jie, Suyun; Sun, Wen-Hua; Chen, Jiutong
Journal of Organometallic Chemistry, 2005 , vol. 690, # 17 p. 3918 - 3928
反应条件
1: CH2Cl2
2: thionyl chloride / toluene
3: NaOH / methanol / Heating
View Scheme
参考文献
Tang, Xiubo; Zhang, Dongheng; Jie, Suyun; Sun, Wen-Hua; Chen, Jiutong
Journal of Organometallic Chemistry, 2005 , vol. 690, # 17 p. 3918 - 3928
反应条件
aluminium trichloride
6 h; Heating;
参考文献
Inamoto, Kiyofumi; Katsuno, Mika; Yoshino, Takashi; Arai, Yukari; Hiroya, Kou; Sakamoto, Takao
Tetrahedron, 2007 , vol. 63, # 12 p. 2695 - 2711
