4-乙酰氧基-3-甲氧基苯甲酰氯合成路线 （共 8 条）
反应条件
1: diazomethane / diethyl ether / -5 - 0 °C 2: water / acetonitrile / 0.17 h / 20 °C / 760.05 Torr / |Irradiation View Scheme
参考文献
Senadheera, Sanjeewa N.; Evans, Anthony S.; Toscano, John P.; Givens, Richard S.
Photochemical and Photobiological Sciences, 2014 , vol. 13, # 2 p. 324 - 341
反应条件
1: pyridine; H2O 2: triethylamine / 160 °C / Erwaermen des Reaktionsprodukts mit wss.-aethanol. Kalilauge View Scheme
参考文献
Deulofeu; Schopflocher
Gazzetta Chimica Italiana, 1953 , vol. 83, p. 449,454
Anales de la Asociacion Quimica Argentina (1921-2001), 1956 , vol. 44, p. 34,39
参考文献
Rosenmund; Zetzsche
Chemische Berichte, 1923 , vol. 56, p. 1483
反应条件
1: diazomethane / diethyl ether / -5 - 0 °C 2: ammonium acetate / water; methanol / 8 h / 50 °C 3: water; biphenyl / acetonitrile / 0.13 h / |Irradiation View Scheme
参考文献
Senadheera, Sanjeewa N.; Evans, Anthony S.; Toscano, John P.; Givens, Richard S.
Photochemical and Photobiological Sciences, 2014 , vol. 13, # 2 p. 324 - 341
反应条件
sodium hydroxide; hydrazine hydrate
参考文献
Libermann et al.
Chemische Berichte, 1954 , p. 1430,1434
反应条件
oxalyl dichloride in benzene
5 h; Heating;
参考文献
McKittrick, Brian A.; Stevenson, Robert
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 2 p. 475 - 482
反应条件
in CH2Cl2 (under a CaSO4 drying tube)
参考文献
3-Dimensional Pharmaceuticals, Inc.
Patent: US6291514 B1, 2001 ;
反应条件
1: Et3N / dimethylformamide
2: SOCl2 / CHCl3 / Heating
View Scheme
参考文献
Gita, Haruhisa; Sobe, Yoshiaki; Akaku, Haruo; Ekine, Rena; Oto, Yuso; Isawa, Satoru; Hayashi, Hideya
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 4 p. 549 - 551
