顺式-11-十六烯-1-醇合成路线 （共 65 条）
反应条件
1: 1.) B2H6, 2.) H2O2/3N NaOH / 1.) diglyme, 5h, 2.) room temperature, overnight 2: H2/RaNi / ethyl acetate / 4 h / 80 °C / 76000.1 Torr 3: 85 percent / PBr3 / benzene / 5 h / Ambient temperature 4: 22 g / acetonitrile / 8 h / Heating 5: 1.) potassium tert-butanolate / 1.) DMF, 20 deg C, 3h, 2.) 5h 6: LiAlH4 / diethyl ether / 3 h / Heating View Scheme
参考文献
Chemistry of Natural Compounds, , vol. 16, # 1 p. 82 - 85
Khimiya Prirodnykh Soedinenii, , vol. 16, # 1 p. 97 - 102
反应条件
1: 1.) potassium tert-butanolate / 1.) DMF, 20 deg C, 3h, 2.) 5h 2: LiAlH4 / diethyl ether / 3 h / Heating View Scheme
参考文献
Chemistry of Natural Compounds, , vol. 16, # 1 p. 82 - 85
Khimiya Prirodnykh Soedinenii, , vol. 16, # 1 p. 97 - 102
反应条件
1: H2/RaNi / ethyl acetate / 4 h / 80 °C / 76000.1 Torr 2: 85 percent / PBr3 / benzene / 5 h / Ambient temperature 3: 22 g / acetonitrile / 8 h / Heating 4: 1.) potassium tert-butanolate / 1.) DMF, 20 deg C, 3h, 2.) 5h 5: LiAlH4 / diethyl ether / 3 h / Heating View Scheme
参考文献
Chemistry of Natural Compounds, , vol. 16, # 1 p. 82 - 85
Khimiya Prirodnykh Soedinenii, , vol. 16, # 1 p. 97 - 102
反应条件
1: 1. t-BuOK / 1. THF, -30 deg C, 15 min, 2. THF, a. -78 deg C, 3 h, b. r.t., 15 h 2: 92 percent / KOH / methanol; H2O / 1. 55 deg C, 7 h, 2. r.t., 15 h 3: 71 percent / Pb(OAc)4, Cu(OAc)2*H2O, pyridine / benzene / 2 h / Heating 4: 1. 9-BBN, 2. 3N NaOH, 26percent H2O2 / 1. THF, r.t., 5 h, 2. r.t., 17 h View Scheme
参考文献
Chemistry of Natural Compounds, , vol. 27, # 1 p. 116 - 118
Khimiya Prirodnykh Soedinenii, , # 1 p. 132 - 135
反应条件
1: 71 percent / Pb(OAc)4, Cu(OAc)2*H2O, pyridine / benzene / 2 h / Heating 2: 1. 9-BBN, 2. 3N NaOH, 26percent H2O2 / 1. THF, r.t., 5 h, 2. r.t., 17 h View Scheme
参考文献
Chemistry of Natural Compounds, , vol. 27, # 1 p. 116 - 118
Khimiya Prirodnykh Soedinenii, , # 1 p. 132 - 135
反应条件
1: 92 percent / KOH / methanol; H2O / 1. 55 deg C, 7 h, 2. r.t., 15 h 2: 71 percent / Pb(OAc)4, Cu(OAc)2*H2O, pyridine / benzene / 2 h / Heating 3: 1. 9-BBN, 2. 3N NaOH, 26percent H2O2 / 1. THF, r.t., 5 h, 2. r.t., 17 h View Scheme
参考文献
Chemistry of Natural Compounds, , vol. 27, # 1 p. 116 - 118
Khimiya Prirodnykh Soedinenii, , # 1 p. 132 - 135
反应条件
2: 86 percent / dil. HCl / diethyl ether / 2.5 h / Ambient temperature 3: 0.91 g / NaBH4 / methanol / 2 h / 0 °C View Scheme
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 28, # 1-11 p. 757 - 759
反应条件
1: 86 percent / dil. HCl / diethyl ether / 2.5 h / Ambient temperature 2: 0.91 g / NaBH4 / methanol / 2 h / 0 °C View Scheme
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 28, # 1-11 p. 757 - 759
反应条件
1: 1) KOH, 2) KOH / 1) methanol, electrolysis, Pt anode, 1.5 F, pH 8.0, 2) ethanol, 5 h 2: 96 percent / LiAlH4 / diethyl ether / 5 h View Scheme
参考文献
Journal of the Indian Chemical Society, , vol. 67, # 7 p. 565 - 567
反应条件
1: 1) KOH, 2) KOH / 1) methanol, electrolysis, Pt anode, 1.5 F, pH 8.0, 2) ethanol, 5 h 2: 96 percent / LiAlH4 / diethyl ether / 5 h View Scheme
参考文献
Journal of the Indian Chemical Society, , vol. 67, # 7 p. 565 - 567
