1: Et3N / toluene / 1 h / 0 °C
2: NaH / diethyl ether; dimethylformamide / 18 h / 20 °C
3: 26 mg / MeI; Na2CO3 / 48 h / Heating
View Scheme
参考文献
Hekking, Koen F. W.; Moelands, Marcel A. H.; Van Delft, Floris L.; Rutjes, Floris P. J. T.
Journal of Organic Chemistry, 2006 , vol. 71, # 17 p. 6444 - 6450
1: NaH / diethyl ether; dimethylformamide / 18 h / 20 °C
2: 26 mg / MeI; Na2CO3 / 48 h / Heating
View Scheme
参考文献
Hekking, Koen F. W.; Moelands, Marcel A. H.; Van Delft, Floris L.; Rutjes, Floris P. J. T.
Journal of Organic Chemistry, 2006 , vol. 71, # 17 p. 6444 - 6450
potassium carbonate in acetone
T=45°C; 0.333333 h; Yield given. Further byproducts given. Yields of byproduct given. Title compound not separated from byproducts;
1: 90 percent / sodium periodate / methanol; H2O / 2 h / 0 °C
2: 80 percent / acetic anhydride, methanesulphonic acid / CH2Cl2 / 24 h / Ambient temperature
View Scheme
参考文献
Foulds, Christopher D.; Jaxa-Chamiec, Albert A.; O'Sullivan, Anthony C.; Sammes, Peter G.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 1 p. 21 - 28
