E. R. Squibb and Sons, Inc.
Patent: US4199512 A1, 1980 ;
US 4199512 A
Title/Abstract Full Text Show Details
E. R. Squibb and Sons, Inc.
Patent: US4339600 A1, 1982 ;
US 4339600 A
1: α-benzyl-acrylic acid With chloroformic acid ethyl ester; triethylamine in dichloromethane
T=-5°C; 0.5 h;
2: glycine benzyl ester p-toluenesulfonic acid salt With triethylamine in dichloromethane
T=-5 - 25°C; 2 h;
3: With sodium hydrogencarbonate in dichloromethane; water
Product distribution / selectivity;
