1: With ethyl bromide; magnesium in tetrahydrofuran
T=35 - 50°C; Inert atmosphere;
2: With anhydrous iron chloride; chloroethylmethylchloride in tetrahydrofuran
T=45 - 65°C; Inert atmosphere;
参考文献
Toray Fine Chemicals Co., Ltd.
Patent: EP2100874 A1, 2009 ;
Location in patent: Page/Page column 6-7 ;
1: 2-CF3C6H4MgX With indium(III) chloride in tetrahydrofuran
T=20°C; 1 h;
2: cyclohex-2-en-1-yl acetate With triphenylphosphine; tris-(dibenzylideneacetone)dipalladium(0) in tetrahydrofuran
Heating;
参考文献
Baker, Lucas; Minehan, Thomas
Journal of Organic Chemistry, 2004 , vol. 69, # 11 p. 3957 - 3960
