[4-(2-甲基苯氧基)苯基]胺合成路线 （共 7 条）
反应条件
hydrogen; palladium on activated charcoal in ethyl acetate T=20°C; Catalytic hydrogenation; P=2280.15 Torr;
参考文献
Szajnman, Sergio H.; Yan, Wen; Bailey, Brian N.; Docampo, Roberto; Elhalem, Eleonora; Rodriguez, Juan B.
Journal of Medicinal Chemistry, 2000 , vol. 43, # 9 p. 1826 - 1840
反应条件
potassium carbonate; 1-(n-1-butyl)-imidazole; copper(l) chloride in n-tetradec-1l-ene; toluene T=120°C; 16 h; Product distribution / selectivity;
参考文献
SALTIGO GMBH
Patent: US2009/143594 A1, 2009 ;
Location in patent: Page/Page column 3; 5 ;
反应条件
copper(l) iodide; potassium carbonate; trans-N,N'-dimethylcyclohexane-1,2-diamine in n-butyronitrile T=70°C; 24 h; Inert atmosphere;
参考文献
Maiti, Debabrata; Buchwald, Stephen L.
Journal of the American Chemical Society, 2009 , vol. 131, # 47 p. 17423 - 17429
反应条件
1: 54 percent / KOH; CuCl / dimethylsulfoxide / 16 h / 20 °C 2: 94 percent / H2 / Pd/C / ethyl acetate / 20 °C / 2280.15 Torr View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 43, # 9 p. 1826 - 1840
反应条件
1: 54 percent / KOH; CuCl / dimethylsulfoxide / 16 h / 20 °C 2: 94 percent / H2 / Pd/C / ethyl acetate / 20 °C / 2280.15 Torr View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 43, # 9 p. 1826 - 1840
反应条件
1: 135 °C 2: tin; hydrochloric acid View Scheme
参考文献
Journal of the American Chemical Society, , vol. 24, p. 1200
反应条件
1: 135 °C 2: tin; hydrochloric acid View Scheme
参考文献
Journal of the American Chemical Society, , vol. 24, p. 1200
