(R)-(+)-阿替洛尔合成路线 （共 13 条）
反应条件
1: Pseudomonas cepacia lipase/diatomite / tetrahydrofuran / 10 h / 20 °C / Enzymatic reaction 2: K2CO3; MeOH View Scheme
参考文献
Synthetic Communications, , vol. 29, # 22 p. 3855 - 3862
反应条件
1: 1.) benzyltrimethylammonium chloride, NaOH / 1.) H2O, 5 deg C, 20 h, 2.) H2O, RT, 8 h 2: 89 percent / MeOH / 12 h / Ambient temperature View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 45, # 2 p. 412 - 414
反应条件
sodium hydroxide; N-benzyl-N,N,N-trimethyl-ammonium chloride 1.) 5 deg C, 20 h, 2.) RT, 12 h; Yield given. Multistep reaction;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 46, # 3 p. 505 - 507
