反应条件
1: 1.) isobutylchloroformate, N-methylmorpholine, 2.) N-methylmorpholine, 3.) bromotrichloromethane / 1.) THF, -15 deg C, 15 min, 2.) THF, -15 deg C, 45 min, 3.) irrad, RT, 3 h 2: 1.) NaBH4, 3.) HCl / 1.) EtOH, 0 deg C, 2.) EtOH, 0 deg C, 20 min 3: 80 percent / O3 / CH2Cl2 / -78 deg C, then 76 deg C, 0.1 h View Scheme
参考文献
Barton, Derek H. R.; Crich, David; Herve, Yolande; Potier, Pierre; Thierry, Josiane
Tetrahedron, 1985 , vol. 41, # 19 p. 4347 - 4358
