4-苯基-2-甲硫基嘧啶合成路线 （共 18 条）
参考文献
Matsukawa; Ohta
Yakugaku Zasshi, 1950 , vol. 70, p. 137
Chem.Abstr., 1950 , p. 5886
反应条件
1: 81 percent / 2 N NaOH / Ambient temperature
2: 69 percent / 18 h / Heating
View Scheme
参考文献
Sansebastiano; Mosti; Menozzi; Schenone; Muratore; Petta; Debbia; Pesce Schito; Schito
Farmaco, 1993 , vol. 48, # 3 p. 335 - 355
反应条件
1: POCl3
2: zinc
View Scheme
参考文献
Matsukawa; Ohta
Yakugaku Zasshi, 1950 , vol. 70, p. 137
Chem.Abstr., 1950 , p. 5886
反应条件
1.1: tetrahydrofuran / 4 h / 20 °C
1.2: 100 percent / 2,3-dicyano-5,6-dichloro-1,4-benzoquinone; aq. AcOH / tetrahydrofuran / 0.75 h / 20 °C
2.1: 100 percent / NiCl2(dppe) / toluene / 4 h / 60 °C
View Scheme
参考文献
Itami, Kenichiro; Yamazaki, Daisuke; Yoshida, Jun-Ichi
Journal of the American Chemical Society, 2004 , vol. 126, # 47 p. 15396 - 15397
反应条件
1.1: tetrahydrofuran / 4 h / 20 °C
1.2: 100 percent / 2,3-dicyano-5,6-dichloro-1,4-benzoquinone; aq. AcOH / tetrahydrofuran / 0.75 h / 20 °C
2.1: 84 percent / NiCl2(dppe) / toluene / 4 h / 60 °C
View Scheme
参考文献
Itami, Kenichiro; Yamazaki, Daisuke; Yoshida, Jun-Ichi
Journal of the American Chemical Society, 2004 , vol. 126, # 47 p. 15396 - 15397
反应条件
1.1: tetrahydrofuran / 4 h / 20 °C
1.2: 100 percent / 2,3-dicyano-5,6-dichloro-1,4-benzoquinone; aq. AcOH / tetrahydrofuran / 0.75 h / 20 °C
2.1: 100 percent / NiCl2(dppe) / toluene / 4 h / 60 °C
View Scheme
参考文献
Itami, Kenichiro; Yamazaki, Daisuke; Yoshida, Jun-Ichi
Journal of the American Chemical Society, 2004 , vol. 126, # 47 p. 15396 - 15397
反应条件
3-chloro-benzenecarboperoxoic acid in dichloromethane
参考文献
American Cyanamid Company
Patent: US4209621 A1, 1980 ;
反应条件
1: in tetrahydrofuran
T=20°C; 4 h;
2: With acetic acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone in tetrahydrofuran
T=20°C; 0.75 h;
参考文献
Itami, Kenichiro; Yamazaki, Daisuke; Yoshida, Jun-Ichi
Journal of the American Chemical Society, 2004 , vol. 126, # 47 p. 15396 - 15397
