4,4-二苯基丁烷-1-醇合成路线 （共 21 条）
反应条件
1: H2 / 5percent Pd/C / ethanol
2: 22 percent / sodium iodide, sodium hydrogen carbonate / dimethylsulfoxide / 2 h / 110 °C
View Scheme
参考文献
N'Goka; Schlewer; Linget; Chambon; Wermuth
Journal of Medicinal Chemistry, 1991 , vol. 34, # 8 p. 2547 - 2557
反应条件
sodium bis(2-methoxyethoxy)aluminium dihydride
参考文献
Rajsner; Kopicova; Holubek; et al.
Collection of Czechoslovak Chemical Communications, 1978 , vol. 43, # 7 p. 1760 - 1777
反应条件
in diethyl ether
0.666667 h; Heating;
参考文献
Maercker, Adalbert; Passlack, Michael
Chemische Berichte, 1983 , vol. 116, # 2 p. 710 - 723
反应条件
1: 180 °C
2: sulfuric acid / CHCl3 / 5 h / Heating
3: lithium aluminum hydride / diethyl ether / 20 °C
View Scheme
参考文献
Schmidt, Matthias; Ungvari, Johannes; Gloede, Julia; Dobner, Bodo; Langner, Andreas
Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 6 p. 2283 - 2297
反应条件
1.1: sulfuric acid / CHCl3 / 5 h / Heating
2.1: lithium aluminum hydride / diethyl ether / 4 h / 20 °C
3.1: triethylamine / CHCl3 / 24 h / 20 °C
4.1: sodium / ethanol
4.2: ethanol / 10 h / Heating
5.1: KOH / ethanol / 10 h / Heating
6.1: 180 °C
7.1: sulfuric acid / CHCl3 / 5 h / Heating
8.1: lithium aluminum hydride / diethyl ether / 20 °C
View Scheme
参考文献
Schmidt, Matthias; Ungvari, Johannes; Gloede, Julia; Dobner, Bodo; Langner, Andreas
Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 6 p. 2283 - 2297
反应条件
1.1: triethylamine / CHCl3 / 24 h / 20 °C
2.1: sodium / ethanol
2.2: ethanol / 10 h / Heating
3.1: KOH / ethanol / 10 h / Heating
4.1: 180 °C
5.1: sulfuric acid / CHCl3 / 5 h / Heating
6.1: lithium aluminum hydride / diethyl ether / 20 °C
View Scheme
参考文献
Schmidt, Matthias; Ungvari, Johannes; Gloede, Julia; Dobner, Bodo; Langner, Andreas
Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 6 p. 2283 - 2297
反应条件
1.1: lithium aluminum hydride / diethyl ether / 4 h / 20 °C
2.1: triethylamine / CHCl3 / 24 h / 20 °C
3.1: sodium / ethanol
3.2: ethanol / 10 h / Heating
4.1: KOH / ethanol / 10 h / Heating
5.1: 180 °C
6.1: sulfuric acid / CHCl3 / 5 h / Heating
7.1: lithium aluminum hydride / diethyl ether / 20 °C
View Scheme
参考文献
Schmidt, Matthias; Ungvari, Johannes; Gloede, Julia; Dobner, Bodo; Langner, Andreas
Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 6 p. 2283 - 2297
反应条件
1.1: sodium / ethanol
1.2: ethanol / 10 h / Heating
2.1: KOH / ethanol / 10 h / Heating
3.1: 180 °C
4.1: sulfuric acid / CHCl3 / 5 h / Heating
5.1: lithium aluminum hydride / diethyl ether / 20 °C
View Scheme
参考文献
Schmidt, Matthias; Ungvari, Johannes; Gloede, Julia; Dobner, Bodo; Langner, Andreas
Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 6 p. 2283 - 2297
反应条件
1: AlCl3
2: Na<AlH2(OCH2CH2OMe)2>
View Scheme
参考文献
Rajsner; Kopicova; Holubek; et al.
Collection of Czechoslovak Chemical Communications, 1978 , vol. 43, # 7 p. 1760 - 1777
反应条件
1: AlCl3
2: Na<AlH2(OCH2CH2OMe)2>
View Scheme
参考文献
Rajsner; Kopicova; Holubek; et al.
Collection of Czechoslovak Chemical Communications, 1978 , vol. 43, # 7 p. 1760 - 1777
