(R)-(-)-2-氯-1-苯乙醇合成路线 （共 34 条）
反应条件
in helium T=130°C; P=750.075 Torr; Chirasil-DEX CB; Resolution of racemateGas phase; Product distribution / selectivity;
参考文献
US2008/234525 A1, ;
Page/Page column 5-6 ;
反应条件
Pseudomonas cepacia lipase immobilized on toyonite; potassium tert-butylate; sodium carbonate; [2,3,4,5-Ph4(η5-C4CNH(i-Pr))]Ru(CO)2Cl in toluene T=25°C; 168 h;
参考文献
Journal of Organic Chemistry, , vol. 69, # 6 p. 1972 - 1977
反应条件
Novozyme[435] in tetrahydrofuran; dimethyl sulfoxide T=30°C; 7 h;
参考文献
Tetrahedron Letters, , vol. 46, # 25 p. 4411 - 4413
反应条件
1: cathecolborane / (5S)-2-(n-butyl)-4,4-diphenyl-3,1,2-oxazaborabicyclo<3.3.0>octane / toluene / 12 h / -78 °C 2: NaCNBH3, AIBN, Bu3SnCl / ethanol / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 34, # 33 p. 5227 - 5230
反应条件
Lipase PS in di-isopropyl ether T=30°C; Esterification; 96 h; Enzymatic reaction; Title compound not separated from byproducts.;
参考文献
Journal of Organic Chemistry, , vol. 65, # 1 p. 83 - 88
反应条件
lipase Amano PS enzyme in di-isopropyl ether T=30°C; 96 h; Yield given. Yields of byproduct given;
参考文献
Tetrahedron Letters, , vol. 37, # 41 p. 7369 - 7372
反应条件
Merulius tremellosus ono991 in acetone T=28°C; 72 h; Title compound not separated from byproducts;
参考文献
Tetrahedron Asymmetry, , vol. 12, # 7 p. 1025 - 1034
反应条件
halohydrin dehalogenase from Agrobacterium radiobacter AD1; Tris-SO4 buffer in water T=30°C; Dehydrochlorination; pH=7.5; Title compound not separated from byproducts;
参考文献
Tetrahedron Asymmetry, , vol. 10, # 15 p. 2863 - 2870
反应条件
2,2'-azo-bisisobutyronitrile; tributyltin chloride; sodium cyanoborohydride in ethanol Heating;
参考文献
Tetrahedron Letters, , vol. 34, # 33 p. 5227 - 5230
反应条件
1: 1-hydroxy-2-chloroethylbenzene With Pseudomonas aeruginosa lipase in isopropyl alcohol T=30°C; 0.5 h; Enzymatic reaction; 2: vinyl acetate in isopropyl alcohol T=30°C; 1 h; Enzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Tetrahedron, , vol. 65, # 46 p. 9583 - 9591
