环丙基-(3-硝基苯基)甲酮合成路线 （共 8 条）
反应条件
nitric acid T=-10°C; 0.166667 h;
参考文献
Journal of Medicinal Chemistry, , vol. 38, # 18 p. 3624 - 3637
反应条件
nitric acid in water T=-40 - -10°C; Cooling with acetone-dry ice;
参考文献
EP1203770 A1, ;
Page 58 ;
参考文献
Journal of Medicinal Chemistry, , vol. 40, # 7 p. 1149 - 1164
反应条件
1: AlCl3 / 35 - 60 °C 2: nitric acid View Scheme
参考文献
Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, , vol. 43, p. 1164
Chem. Zentralbl., , vol. 83, # I p. 1458
参考文献
Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, , vol. 43, p. 1164
Chem. Zentralbl., , vol. 83, # I p. 1458
反应条件
1: hydrogen / 5percent platinum on carbon / methanol / 5 h / 760 Torr 2: diisopropylethylamine / CH2Cl2 / 4 h / Ambient temperature View Scheme
参考文献
Thaisrivongs, Suvit; Watenpaugh, Keith D.; Howe, W. Jeffrey; Tomich, Paul K.; Dolak, Lester A.; et al.
Journal of Medicinal Chemistry, 1995 , vol. 38, # 18 p. 3624 - 3637
反应条件
hydrogen; platinum on activated charcoal in methanol P=760 Torr; 5 h;
参考文献
PHARMACIA and UPJOHN COMPANY
Patent: EP1203770 A1, 2002 ;
Location in patent: Page 58 ;
参考文献
Kishner
Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, 1911 , vol. 43, p. 1164
Chem. Zentralbl., 1912 , vol. 83, # I p. 1458
