4-氯-6-甲基喹啉-3-甲酸乙酯合成路线 (共 7 条)
反应条件
thionyl chloride 17 h; Heating;
参考文献
Nucleosides, Nucleotides and Nucleic Acids, , vol. 23, # 5 p. 735 - 748
反应条件
trichlorophosphate T=110°C; 0.333333 h; Inert atmosphere;
参考文献
Goncalves, Victor; Brannigan, James A.; Whalley, David; Ansell, Keith H.; Saxty, Barbara; Holder, Anthony A.; Wilkinson, Anthony J.; Tate, Edward W.; Leatherbarrow, Robin J.
Journal of Medicinal Chemistry, 2012 , vol. 55, # 7 p. 3578 - 3582
反应条件
1: 2 h / 110 - 115 °C 2: various solvent(s) / 0.5 h / 250 °C 3: 71 percent / POCl3 / 5 h / Heating View Scheme
参考文献
Farmaco, , vol. 53, # 8-9 p. 579 - 585
反应条件
1: various solvent(s) / 0.5 h / 250 °C 2: 71 percent / POCl3 / 5 h / Heating View Scheme
参考文献
Farmaco, , vol. 53, # 8-9 p. 579 - 585
反应条件
1: ethanol / Reflux 2: diphenylether / Reflux 3: thionyl chloride / 17 h / Reflux View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 46, # 4 p. 1448 - 1452
反应条件
1: |Heating 2: thionyl chloride / |Heating View Scheme
参考文献
Journal of Molecular Structure, , vol. 1051, p. 299 - 309
反应条件
1: in toluene
3 h;
2: With acetic acid
2 h; Heating;
参考文献
De Oliveira, Mara R. P.; Alves, Thatyana R.; Pinto, Angelo C.; Pereira, Helena De S.; Leao-Ferreira, Luiz R.; Moussatche, Nissin; Frugulhetti, Izabel Christina De P. P.; Ferreira, Vitor F.; De Souza, Maria Cecilia B. V.
Nucleosides, Nucleotides and Nucleic Acids, 2004 , vol. 23, # 5 p. 735 - 748