2-甲基噻吩并[2,3-d]嘧啶合成路线 （共 8 条）
反应条件
hydrogen sulfide; sodium ethanolate in ethanol
1.5 h; Heating;
参考文献
Sakamoto, Takao; Kondo, Yoshinori; Watanabe, Ryo; Yamanaka, Hiroshi
Chemical & Pharmaceutical Bulletin, 1986 , vol. 34, # 7 p. 2719 - 2724
反应条件
1: 46 percent / I2 / HNO3 / 6 h / 80 °C
2: 82 percent / POCl3 / Heating
3: 77 percent / Pd(PPh3)2Cl2, CuI, Et3N / 12 h / 80 °C
4: 73 percent / NaOEt, H2S / ethanol / 1.5 h / Heating
View Scheme
参考文献
Sakamoto, Takao; Kondo, Yoshinori; Watanabe, Ryo; Yamanaka, Hiroshi
Chemical & Pharmaceutical Bulletin, 1986 , vol. 34, # 7 p. 2719 - 2724
反应条件
1: 77 percent / Pd(PPh3)2Cl2, CuI, Et3N / 12 h / 80 °C
2: 73 percent / NaOEt, H2S / ethanol / 1.5 h / Heating
View Scheme
参考文献
Sakamoto, Takao; Kondo, Yoshinori; Watanabe, Ryo; Yamanaka, Hiroshi
Chemical & Pharmaceutical Bulletin, 1986 , vol. 34, # 7 p. 2719 - 2724
反应条件
1: 82 percent / POCl3 / Heating
2: 77 percent / Pd(PPh3)2Cl2, CuI, Et3N / 12 h / 80 °C
3: 73 percent / NaOEt, H2S / ethanol / 1.5 h / Heating
View Scheme
参考文献
Sakamoto, Takao; Kondo, Yoshinori; Watanabe, Ryo; Yamanaka, Hiroshi
Chemical & Pharmaceutical Bulletin, 1986 , vol. 34, # 7 p. 2719 - 2724
反应条件
mercury(II) oxide in water
参考文献
Bourguignon,J. et al.
Bulletin de la Societe Chimique de France, 1975 , p. 815 - 819
反应条件
1: N2H4 / ethanol / Heating
2: HgO / H2O
View Scheme
参考文献
Bourguignon,J. et al.
Bulletin de la Societe Chimique de France, 1975 , p. 815 - 819
反应条件
1: POCl3, Py / Heating
2: N2H4 / ethanol / Heating
3: HgO / H2O
View Scheme
参考文献
Bourguignon,J. et al.
Bulletin de la Societe Chimique de France, 1975 , p. 815 - 819
反应条件
oxygen; sodium ethanolate
参考文献
Robba,M.; Cugnon de Sevricourt,M.
Bulletin de la Societe Chimique de France, 1976 , p. 761 - 764
