triethylamine in tetrahydrofuran; water

1: With benzotriazol-1-ol; triethylamine in dichloromethane 0.25 h; Cooling with ice; 2: With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride in dichloromethane T=20°C; Cooling with ice;

1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 21 °C / Inert atmosphere 2: dichloromethane / -40 - -10 °C / Inert atmosphere View Scheme

in dichloromethane T=-40 - -10°C; Inert atmosphere;