Multistep reaction;

1: 96 percent / t-BuOK / dimethylformamide / 14 h / 0 - 20 °C 2: 70 percent / NaH, (Ph3P)4Pd / tetrahydrofuran / 2 h / Ambient temperature 3: 88 percent / K2CO3 / methanol / 1.25 h 4: 87 percent / Cs2CO3, C6H5SH / dimethylformamide / 4.25 h / 90 °C 5: 58 percent / PdCl2dppp, LiBHEt3 / tetrahydrofuran / 1 h / 0 °C View Scheme

1.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C / Inert atmosphere 1.2: 2 h / -78 °C / Inert atmosphere 2.1: pyridinium p-toluenesulfonate / dichloromethane / 2 h / 0 °C / Inert atmosphere 3.1: Pd(1,2-bis(diphenylphosphino)ethane)Cl2; lithium triethylborohydride / tetrahydrofuran; 1,4-dioxane / 10 h / 20 - 70 °C / Inert atmosphere View Scheme

1.1: potassium tert-butylate / tetrahydrofuran / 1 h / -30 °C / Inert atmosphere 1.2: Inert atmosphere 2.1: Pd(1,3-bis(diphenylphosphino)-propane)Cl2; lithium triethylborohydride / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere View Scheme