2,3,5,6-四氢-5-(4-氟苯基)咪唑并[2,1-a]异喹啉-5-醇合成路线 （共 2 条）
反应条件
n-butyllithium; sodium carbonate in tetrahydrofuran; methanol; dichloromethane methylalcohol; hexane; water; acetic acid
参考文献
Sandoz Pharmaceuticals Corp.
Patent: US4910206 A1, 1990 ;
US 4910206 A
反应条件
n-butyllithium
1.) THF, hexane, 35 deg C, 4 h, 2.) THF, hexane, -20 deg C, 3 h; Yield given. Multistep reaction;
参考文献
Houlihan; Gogerty; Parrino; Ryan
Journal of Medicinal Chemistry, 1983 , vol. 26, # 5 p. 765 - 768
