5-环己基-1,3,4-噻二唑-2-胺合成路线 （共 4 条）
反应条件
1: With hydrogenchloride in water 3 h; Heating / reflux; 2: With sodium hydroxide in water T=0 - 20°C; pH=8 - 9; 0.25 h;
参考文献
SMITHKLINE BEECHAM CORPORATION
Patent: WO2008/70707 A1, 2008 ;
Location in patent: Page/Page column 25 ;
WO 2008/070707 A1
反应条件
pyridine; sulfuric acid
参考文献
Farmaco, Edizione Scientifica, , vol. 13, p. 187,196
反应条件
sodium chloride; sodium nitrite in water; hydrogen bromide
参考文献
Sanofi
Patent: US4596802 A1, 1986 ;
