4-(2-溴乙酰基)苯甲酸甲酯合成路线

56893-25-54-(2-溴乙酰基)苯甲酸甲酯

1011716-95-22-氨基-5-(4-(甲氧基羰基)苯基)-1H-吡咯-3-羧酸乙酯

参考文献

CURIS, INC.
Patent: WO2008/33745 A2, 2008 ;
Location in patent: Page/Page column 71 ;
WO 2008/033745 A2

57508-48-22-脒基乙酸乙酯盐酸盐+

56893-25-54-(2-溴乙酰基)苯甲酸甲酯

1011716-95-22-氨基-5-(4-(甲氧基羰基)苯基)-1H-吡咯-3-羧酸乙酯

参考文献

CURIS, INC.
Patent: WO2008/33747 A2, 2008 ;
Location in patent: Page/Page column 255 ;

64-17-5乙醇+

57508-48-22-脒基乙酸乙酯盐酸盐+

56893-25-54-(2-溴乙酰基)苯甲酸甲酯

1011716-95-22-氨基-5-(4-(甲氧基羰基)苯基)-1H-吡咯-3-羧酸乙酯

参考文献

ADVINUS THERAPEUTICS LIMITED; THAKKAR, Mahesh; KOUL, Summon; BHUNIYA, Debnath; MOOKHTIAR, Kasim; KURHADE, Santosh; MUNOT, Yogesh
Patent: WO2013/157022 A1, 2013 ;
Location in patent: Page/Page column 70 ;

56893-25-54-(2-溴乙酰基)苯甲酸甲酯

333737-29-44-(5-氨基-1H-吡唑-3-基)苯甲酸甲酯

参考文献

Hou, Zengye; Nakanishi, Isao; Kinoshita, Takayoshi; Takei, Yoshinori; Yasue, Misato; Misu, Ryosuke; Suzuki, Yamato; Nakamura, Shinya; Kure, Tatsuhide; Ohno, Hiroaki; Murata, Katsumi; Kitaura, Kazuo; Hirasawa, Akira; Tsujimoto, Gozoh; Oishi, Shinya; Fujii, Nobutaka
Journal of Medicinal Chemistry, 2012 , vol. 55, # 6 p. 2899 - 2903

56893-25-54-(2-溴乙酰基)苯甲酸甲酯+

17356-08-0

206555-77-34-(2-氨基-4-噻唑基)苯甲酸甲酯

参考文献

DAIICHI PHARMACEUTICAL CO., LTD.
Patent: EP1577302 A1, 2005 ;
Location in patent: Page/Page column 109 ;

56893-25-54-(2-溴乙酰基)苯甲酸甲酯

206555-77-34-(2-氨基-4-噻唑基)苯甲酸甲酯

参考文献

DAIICHI PHARMACEUTICAL CO., LTD.
Patent: EP1104754 A1, 2001 ;

56893-25-54-(2-溴乙酰基)苯甲酸甲酯+

131-91-91-亚硝基-2-萘酚

5516-26-7

参考文献

Aljaar, Nayyef; Malakar, Chandi C.; Conrad, Ju Rgen; Frey, Wolfgang; Beifuss, Uwe
Journal of Organic Chemistry, 2013 , vol. 78, # 1 p. 154 - 166

91-19-0喹喔啉+

56893-25-54-(2-溴乙酰基)苯甲酸甲酯

6278-36-0

参考文献

Cytovia, Inc.
Patent: US2005/14759 A1, 2005 ;
Location in patent: Page/Page column 9; 20 ;
US 20050014759 A1