6,7-二甲氧基-1(3h)-异苯并呋喃酮合成路线 （共 82 条）
反应条件
hydrogenchloride T=70 - 80°C; 3 h;
参考文献
Ogawa, Yoshimitsu; Hosaka, Kunio; Chin, Masao; Mitsuhashi, Hiroshi
Heterocycles, 1991 , vol. 32, # 9 p. 1737 - 1744
反应条件
methanol; trifluoroacetic acid in tetrahydrofuran; pentane 36 h; Ambient temperature; Yield given;
参考文献
Journal of Organic Chemistry, , vol. 57, # 7 p. 2029 - 2033
反应条件
1: NaBH4 / methanol 2: 1.) NaH / 1.) DMF, 0 deg C, 2.) rt, 3 h 3: 1.) t-BuLi, 2.) methanol / 1.) THF, pentane, -100 to -95 deg C, 30 min, 2.) rt 4: methanol, trifluoroacetic acid / tetrahydrofuran; pentane / 36 h / Ambient temperature View Scheme
参考文献
Journal of Organic Chemistry, , vol. 57, # 7 p. 2029 - 2033
反应条件
1: 1.) NaH / 1.) DMF, 0 deg C, 2.) rt, 3 h 2: 1.) t-BuLi, 2.) methanol / 1.) THF, pentane, -100 to -95 deg C, 30 min, 2.) rt 3: methanol, trifluoroacetic acid / tetrahydrofuran; pentane / 36 h / Ambient temperature View Scheme
参考文献
Journal of Organic Chemistry, , vol. 57, # 7 p. 2029 - 2033
反应条件
1: 1.) t-BuLi, 2.) methanol / 1.) THF, pentane, -100 to -95 deg C, 30 min, 2.) rt 2: methanol, trifluoroacetic acid / tetrahydrofuran; pentane / 36 h / Ambient temperature View Scheme
参考文献
Journal of Organic Chemistry, , vol. 57, # 7 p. 2029 - 2033
反应条件
1: 70 percent / Br2 / acetic acid / 1.5 h / 20 - 25 °C 2: 96 percent / KOH / H2O / 15 h / 50 °C 4: 94 percent / NaBH4 / ethanol / 1.)2 h, 0-5 deg C, 2.) 12 h, 25 deg C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 48, # 14 p. 2356 - 2360
反应条件
1: 96 percent / KOH / H2O / 15 h / 50 °C 3: 94 percent / NaBH4 / ethanol / 1.)2 h, 0-5 deg C, 2.) 12 h, 25 deg C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 48, # 14 p. 2356 - 2360
反应条件
sodium amalgam; water nachfolgendes Ansaeuern;
参考文献
Journal of the Chemical Society, , vol. 16, p. 347
Justus Liebigs Annalen der Chemie, , vol. Suppl.1, p. 332
反应条件
1: 1) s-BuLi, N,N,N,N-tetramethylethylene diamine / 1) THF, cyclohexane, -78 deg C, 1 h, 2) to room temperature, 12 h 2: NaBH4 / methanol / 3 h 3: aq. 2 N HCl / methanol / 1 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 48, # 23 p. 4863 - 4878
反应条件
1: NaBH4 / methanol / 3 h 2: aq. 2 N HCl / methanol / 1 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 48, # 23 p. 4863 - 4878
