(9ci)-1H-2-苯并吡喃-1,4(3h)-二酮合成路线 （共 19 条）
反应条件
ammonium acetate in acetic acid T=60°C; 6 h;
参考文献
Barcia, Jose C; Cruces, Jacobo; Estevez, Juan C; Estevez, Ramon J; Castedo, Luis
Tetrahedron Letters, 2002 , vol. 43, # 29 p. 5141 - 5144
反应条件
1: With hydrogen bromide; bromine; acetic acid in chlorobenzene
T=30°C; 3 h;
2: With water in chlorobenzene
3 h; Reflux;
参考文献
GLAXO GROUP LIMITED; DWYER, Andrew Neil; GORDON, Andrew; URQUHART, Michael
Patent: WO2012/80243 A2, 2012 ;
Location in patent: Page/Page column 15-16 ;
反应条件
sodium acetate in ethanol
T=20°C; 0.5 h;
参考文献
Barcia, Jose C; Cruces, Jacobo; Estevez, Juan C; Estevez, Ramon J; Castedo, Luis
Tetrahedron Letters, 2002 , vol. 43, # 29 p. 5141 - 5144
反应条件
perchloric acid; water
T=20°C; other reagent, kinetic solvent isotope effect; Rate constantProduct distribution;
参考文献
Kirkovskii, L. I.; Chapishev, S. V.
Doklady Chemistry, 1986 , vol. 291, p. 477 - 480
Dokl. Akad. Nauk SSSR Ser. Khim., 1986 , vol. 291, # 4 p. 874 - 877
反应条件
copper acetylacetonate in benzene
Heating;
参考文献
Ibata, Toshikazu; Jitsuhiro, Kimiko; Tsubokura, Yoshie
Bulletin of the Chemical Society of Japan, 1981 , vol. 54, # 1 p. 240 - 244
反应条件
copper acetylacetonate in benzene
Heating;
参考文献
Ibata, Toshikazu; Jitsuhiro, Kimiko; Tsubokura, Yoshie
Bulletin of the Chemical Society of Japan, 1981 , vol. 54, # 1 p. 240 - 244
反应条件
1: diethyl ether
2: dil. H2SO4
View Scheme
参考文献
Ishikawa, Masayuki; Eguchi, Yukuo
Heterocycles, 1981 , vol. 16, # 1 p. 25 - 30
反应条件
copper acetylacetonate in benzene
Heating;
参考文献
Ibata, Toshikazu; Jitsuhiro, Kimiko; Tsubokura, Yoshie
Bulletin of the Chemical Society of Japan, 1981 , vol. 54, # 1 p. 240 - 244
反应条件
1.1: triethylamine / 10 h / 80 °C
1.2: 0.5 h
2.1: bromine; hydrogen bromide; acetic acid / chlorobenzene / 3 h / 30 °C
2.2: 3 h / Reflux
View Scheme
参考文献
GLAXO GROUP LIMITED; DWYER, Andrew Neil; GORDON, Andrew; URQUHART, Michael
Patent: WO2012/80243 A2, 2012 ;
反应条件
boron trifluoride diethyl etherate in methanol
Yield given. Yields of byproduct given;
参考文献
Miller, R. D.; Theis, W.
Tetrahedron Letters, 1987 , vol. 28, # 10 p. 1039 - 1042
