3-甲氧基-5,6-开环雌甾-1,3,5(10),8,14-五烯-17-酮合成路线 （共 10 条）
反应条件
1: 60 percent / HOAc / xylene / 7 h / Heating
2: 80 percent / H2 / 10percent Pd-C / ethanol / 0.25 h / 775.7 Torr
3: 35 percent / TosOH / benzene / 2 h / Heating
View Scheme
参考文献
Jayaraman, S.; Raju, N.; Rajagopalan, K.
Steroids, 1982 , vol. 40, # 3 p. 267 - 274
反应条件
toluene-4-sulfonic acid in benzene
2 h; Heating;
参考文献
Jayaraman, S.; Raju, N.; Rajagopalan, K.
Steroids, 1982 , vol. 40, # 3 p. 267 - 274
反应条件
1: 75 percent / pyridinium dichromate / CH2Cl2 / 24 h
2: 73 percent / tetrahydrofuran / 1) -70 deg C, 1 h, 2) 0 deg C, 2 h, 3) reflux, 2 h
3: 60 percent / HOAc / xylene / 7 h / Heating
4: 80 percent / H2 / 10percent Pd-C / ethanol / 0.25 h / 775.7 Torr
5: 35 percent / TosOH / benzene / 2 h / Heating
View Scheme
参考文献
Jayaraman, S.; Raju, N.; Rajagopalan, K.
Steroids, 1982 , vol. 40, # 3 p. 267 - 274
反应条件
1: 73 percent / tetrahydrofuran / 1) -70 deg C, 1 h, 2) 0 deg C, 2 h, 3) reflux, 2 h
2: 60 percent / HOAc / xylene / 7 h / Heating
3: 80 percent / H2 / 10percent Pd-C / ethanol / 0.25 h / 775.7 Torr
4: 35 percent / TosOH / benzene / 2 h / Heating
View Scheme
参考文献
Jayaraman, S.; Raju, N.; Rajagopalan, K.
Steroids, 1982 , vol. 40, # 3 p. 267 - 274
反应条件
1: 60 percent / HOAc / xylene / 7 h / Heating
2: 80 percent / H2 / 10percent Pd-C / ethanol / 0.25 h / 775.7 Torr
3: 35 percent / TosOH / benzene / 2 h / Heating
View Scheme
参考文献
Jayaraman, S.; Raju, N.; Rajagopalan, K.
Steroids, 1982 , vol. 40, # 3 p. 267 - 274
反应条件
1: 80 percent / H2 / 10percent Pd-C / ethanol / 0.25 h / 775.7 Torr
2: 35 percent / TosOH / benzene / 2 h / Heating
View Scheme
参考文献
Jayaraman, S.; Raju, N.; Rajagopalan, K.
Steroids, 1982 , vol. 40, # 3 p. 267 - 274
反应条件
toluene-4-sulfonic acid in benzene
参考文献
Bindra,J.S. et al.
Journal of Medicinal Chemistry, 1975 , vol. 18, p. 921 - 925
反应条件
2: KOH / propan-2-ol
3: TsOH / benzene
View Scheme
参考文献
Bindra,J.S. et al.
Journal of Medicinal Chemistry, 1975 , vol. 18, p. 921 - 925
反应条件
1: KOH / propan-2-ol
2: TsOH / benzene
View Scheme
参考文献
Bindra,J.S. et al.
Journal of Medicinal Chemistry, 1975 , vol. 18, p. 921 - 925
反应条件
1: (i) Mg, Et2O, (ii) /BRN= 908286/
3: KOH / propan-2-ol
4: TsOH / benzene
View Scheme
参考文献
Bindra,J.S. et al.
Journal of Medicinal Chemistry, 1975 , vol. 18, p. 921 - 925
