lithium aluminium tetrahydride in tetrahydrofuran T=0 - 20°C;

lithium aluminium tetrahydride in tetrahydrofuran Reduction;

1: 90 percent / TMSCl / CH2Cl2 / Heating 2: 80 percent / LiAlH4 / tetrahydrofuran / Heating View Scheme

1: boron trifluoride diethyl etherate / dichloromethane / 0 - 20 °C 2: lithium aluminium tetrahydride / tetrahydrofuran / 0 - 20 °C View Scheme

1: triphenylphosphine; bromine; triethylamine / dichloromethane / 50 h / 0 - 20 °C / |Inert atmosphere 2: N,N'-dimethyl-N,N'-propyleneurea; lithium diisopropyl amide / tetrahydrofuran / -40 - 0 °C / |Inert atmosphere 3: tetrabutyl ammonium fluoride / tetrahydrofuran / 0 °C / |Inert atmosphere 4: 1-methyl-1H-imidazole / tetrahydrofuran / 0 °C / |Inert atmosphere 5: 1,10-phenanthroline; n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C / |Inert atmosphere View Scheme