2,5-二氯-3-氯磺酰基噻吩合成路线 (共 2 条)
反应条件
chlorosulfonic acid; thionyl chloride 2 h; Ambient temperature;
参考文献
Journal of Medicinal Chemistry, , vol. 40, # 6 p. 980 - 989
反应条件
ammonium hydroxide in water T=100°C; 0.5 h;
参考文献
Abu-El-Halawa, Rajab; Masad, Mohanad; Bathich, Yaser; Al-Refai, Mahmoud; Ibrahim, Mohammad M.; El-Abadelah, Mustafa M.; Voelter, Wolfgang
Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 2011 , vol. 66, # 7 p. 715 - 720