5-(苄氧基)-2-羟基苯甲醛合成路线 （共 17 条）
反应条件
potassium carbonate in acetone T=20°C; 8 h; Schlenk techniqueGlovebox;
参考文献
Wang, Xiaoming; Wang, Xubin; Guo, Peihua; Wang, Zheng; Ding, Kuiling
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 14-15 p. 2900 - 2907
反应条件
caesium carbonate in DMF (N,N-dimethyl-formamide) T=80°C; 18 h;
参考文献
ELI LILLY AND COMPANY
Patent: WO2004/63184 A1, 2004 ;
Location in patent: Page 43 ;
WO 2004/063184 A1
反应条件
caesium carbonate in DMF (N,N-dimethyl-formamide) T=80°C; 18 h;
参考文献
ELI LILLY AND COMPANY
Patent: WO2005/66136 A1, 2005 ;
Location in patent: Page/Page column 42-43 ;
WO 2005/066136 A1
反应条件
magnesium bromide in diethyl ether; benzene
8 h; Heating;
参考文献
Hayashi, Ken-ichiro; Yamazoe, Atsushi; Ishibashi, Yuki; Kusaka, Naoyuki; Oono, Yutaka; Nozaki, Hiroshi
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 9 p. 5331 - 5344
反应条件
sodium hydrogencarbonate; potassium iodide in acetonitrile
30 h; Reflux;
参考文献
Zhang, Bei; Zhao, Yanfang; Zhai, Xin; Wang, Lihui; Yang, Jingyu; Tan, Zehui; Gong, Ping
Chemical and Pharmaceutical Bulletin, 2012 , vol. 60, # 8 p. 1046 - 1054
反应条件
ozone in methanol
T=-78°C; Oxidation; 0.0833333 h;
参考文献
Cho, Young Jin; Lee, Seung Hwan; Bae, Jong Woo; Pyun, Hyung-Jung; Yoon, Cheol Min
Tetrahedron Letters, 2000 , vol. 41, # 20 p. 3915 - 3917
反应条件
hydrogenchloride; sodium hydroxide in ethanol; chloroform
参考文献
Ciba-Geigy Corporation
Patent: US5155130 A1, 1992 ;
US 5155130 A
反应条件
sodium hydrogencarbonate; potassium iodide in acetonitrile
24 h; Heating;
参考文献
Barrero, Alejandro F.; Quilez del Moral, Jose F.; Mar Herrador; Arteaga, Pilar; Cortes, Manuel; Benites, Julio; Rosellon, Antonio
Tetrahedron, 2006 , vol. 62, # 25 p. 6012 - 6017
反应条件
1: 90 percent / ethanol / Heating
2: 85 percent / K2CO3 / acetonitrile / Heating
3: 74 percent / O3 / methanol / 0.08 h / -78 °C
View Scheme
参考文献
Cho, Young Jin; Lee, Seung Hwan; Bae, Jong Woo; Pyun, Hyung-Jung; Yoon, Cheol Min
Tetrahedron Letters, 2000 , vol. 41, # 20 p. 3915 - 3917
反应条件
1: 85 percent / K2CO3 / acetonitrile / Heating
2: 74 percent / O3 / methanol / 0.08 h / -78 °C
View Scheme
参考文献
Cho, Young Jin; Lee, Seung Hwan; Bae, Jong Woo; Pyun, Hyung-Jung; Yoon, Cheol Min
Tetrahedron Letters, 2000 , vol. 41, # 20 p. 3915 - 3917
