反应条件
1: 1) t-BuOK / 1) CH2Cl2, -15 deg C, 10 min, 2) CH2Cl2, 0 deg C, 1 h 2: 98 percent / i-Pr2NH, POCl3 / tetrahydrofuran / 1 h / -30 °C 3: 93 percent / NaBH4 / tetrahydrofuran; ethanol / 3 h / 20 °C 4: 1) t-BuOK / 1) THF, -40 deg C, 10 min, 2a) -40 deg C, 15 min, 2b) to 0 deg C 5: 5 percent aq. HClO4 / dioxane / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 57, # 8 p. 2249 - 2252
