3α,17α-Dihydroxy-5β-pregnan-20-one合成路线 (共 3 条)
反应条件
1: Br2 2: NaBH4 / dimethylformamide View Scheme
参考文献
Lewbart
The Journal of organic chemistry, 1968 , vol. 33, # 5 p. 1695 - 1706
反应条件
mit Hilfe von Rattenleber-Praeparaten;
参考文献
De Courcy; Schneider
Journal of Biological Chemistry, 1956 , vol. 223, p. 865,871
反应条件
human 20α-hydroxysteroid dehydrogenase (AKR1C1) mutant enzyme Leu308Val; NADP T=25°C; pH=7.4; aq. phosphate bufferEnzymatic reaction; Kinetics;
参考文献
Dhagat, Urmi; Endo, Satoshi; Soda, Midori; Hara, Akira; El-Kabbani, Ossama
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 17 p. 5274 - 5276