1: 95 percent / (i-Pr)2NEt / tetrahydrofuran / 0.08 h / -78 °C 2: 95 percent / pyridine, POCl3 / 18 h / Ambient temperature 3: 69 mg / Bu4NF / tetrahydrofuran / 8 h / Ambient temperature 4: 18 h / Heating View Scheme

Erwaermen des Reaktionsprodukts mit Acetanhydrid und Pyridin;

1: 15 percent / imidazole, sodium hydride / tetrahydrofuran / 0.5 h / Heating 2: 79 percent / K, t-BuNH2, 18-crown-6 / tetrahydrofuran 3: 91 percent / pyridine / CH2Cl2 / 17 h / 50 °C 4: 73 percent / sodium-potassium eutectic, 18-crown-6, t-BuNH2 / tetrahydrofuran View Scheme

1: 95 percent / (i-Pr)2NEt / tetrahydrofuran / 0.08 h / -78 °C 2: 95 percent / pyridine, POCl3 / 18 h / Ambient temperature 3: 69 mg / Bu4NF / tetrahydrofuran / 8 h / Ambient temperature View Scheme

1: 15 percent / imidazole, sodium hydride / tetrahydrofuran / 0.5 h / Heating 2: 79 percent / K, t-BuNH2, 18-crown-6 / tetrahydrofuran View Scheme

1: 100 percent / pyridine / CHCl3 / 17 h / 23 °C 2: 31 percent / pyridine / 24 h / 23 °C View Scheme