2-氯-4-甲氧基-5-溴嘧啶合成路线 （共 3 条）
反应条件
methanol T=20°C; 4 h;
参考文献
Almirall, S.A.; Eastwood, Paul Robert; Gonzalez Rodriguez, Jacob; Bach Taña, Jordi; Pages Santacana, Lluis Miquel; Taltavull Moll, Joan; Caturla Javaloyes, Juan Francisco
Patent: EP2338888 A1, 2011 ;
Location in patent: Paragraph 0173; 0174 ;
EP 2338888 A1
反应条件
ammonium formate; palladium 10 on activated carbon in methanol T=20°C; 3 h;
参考文献
ASTRAZENECA AB
Patent: US2008/318943 A1, 2008 ;
Location in patent: Page/Page column 74-75 ;
US 20080318943 A1
反应条件
in tetrahydrofuran
T=20 - 45°C; 0.5 h;
参考文献
Amgen Inc.
Patent: US2006/199817 A1, 2006 ;
Location in patent: Page/Page column 49 ;
US 20060199817 A1
