顺式-5-氮杂-4-氧代-辛-2-烯-二酸合成路线 （共 7 条）
反应条件
2,4,6-trimethyl-pyridine in N,N-dimethyl-formamide T=0 - 20°C;
参考文献
Paterson, Michael J.; Eggleston, Ian M.
Synthetic Communications, 2008 , vol. 38, # 2 p. 303 - 308
反应条件
dicyclohexyl-carbodiimide in tetrahydrofuran; N,N-dimethyl-formamide 1.) -15 deg C, 2 h; 2.) r. t., 3 h;
参考文献
Augustin, Manfred; Mueller, Wolfgang
Journal fuer Praktische Chemie (Leipzig), 1985 , vol. 327, # 5 p. 789 - 798
反应条件
1: 12 percent / Et3N / toluene / 4 h / Heating 2: DCC / CH2Cl2 / 0.33 h / 20 °C View Scheme
参考文献
Veprek, Pavel; Hajduch, Marian; Dzubak, Petr; Kuklik, Rostislav; Polakova, Jana; Bezouska, Karel
Journal of Medicinal Chemistry, 2006 , vol. 49, # 21 p. 6400 - 6407
反应条件
triethylamine in toluene Condensation; 4 h; Heating;
参考文献
Parvez, Masood; Ali, Saqib; Bhatti, Moazzam Hussain; Khokhar, Muhammad Nawaz; Mazhar, Muhammad; Qureshi, Sajid Iqbal
Acta Crystallographica Section C: Crystal Structure Communications, 1999 , vol. 55, # 9 p. 1427 - 1429
反应条件
1: 2.74 g / AcOH / 8 h / Heating 2: 96 percent / Cs2CO3 / dimethylformamide / 16 h / 20 °C View Scheme
参考文献
Pearson, Russell J.; Kassianidis, Eleftherios; Slawin, Alexandra M.Z.; Philp, Douglas
Organic and Biomolecular Chemistry, 2004 , vol. 2, # 23 p. 3434 - 3441
反应条件
triethylamine in toluene 4 h; Heating;
参考文献
Veprek, Pavel; Hajduch, Marian; Dzubak, Petr; Kuklik, Rostislav; Polakova, Jana; Bezouska, Karel
Journal of Medicinal Chemistry, 2006 , vol. 49, # 21 p. 6400 - 6407
反应条件
thionyl chloride Heating;
参考文献
Li, Xiaoxu; Taylor, John Stephen
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 3 p. 545 - 552
