4-羟基-2-甲基苯甲酸乙酯合成路线 （共 14 条）
反应条件
1: 70 percent / sodium hydride / dimethylformamide / 5 h / 75 °C
2: 52 g / iodine/periodic acid / acetic acid; H2O; H2SO4 / 6 h
3: 1.) butyl-lithium / 1.) ether/hexane, -70 deg C, 45 min; 2.) ether/hexane
4: hydrobromic acid / aq. acetic acid / Heating
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参考文献
Cornforth, Sir John; Kumar, Ashok; Stuart, Alan S.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1987 , p. 859 - 866
反应条件
96 h; Ambient temperature;
参考文献
Baker, Murray V.; Ghitgas, Christine; Haynes, Richard K.; Hilliker, Audrey E.; Lynch, Gregory J.; et al.
Australian Journal of Chemistry, 1984 , vol. 37, # 10 p. 2037 - 2058
参考文献
Claisen
Justus Liebigs Annalen der Chemie, 1897 , vol. 297, p. 57
Chemische Berichte, 1893 , vol. 26, p. 2731
反应条件
2: beim Erhitzen ueber den Schmelzpunkt
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参考文献
Gomberg; Johnson
Journal of the American Chemical Society, 1917 , vol. 39, p. 1680
