(3-溴苯氧基)三异丙基硅烷合成路线 （共 6 条）
反应条件
1: 100 percent / Pd(OAc)2; P(tBu)3; NaOtBu / toluene 2: 100 percent / tetrabutylammonium fluoride / tetrahydrofuran View Scheme
参考文献
Matasi, Julius J.; Caldwell, John P.; Zhang, Hongtao; Fawzi, Ahmad; Higgins, Guy A.; Cohen-Williams, Mary E.; Varty, Geoffrey B.; Tulshian, Deen B.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 16 p. 3675 - 3678
反应条件
1: 100 percent / Pd(OAc)2; P(tBu)3; NaOtBu / toluene 2: 100 percent / tetrabutylammonium fluoride / tetrahydrofuran 3: 80 percent / Et3N / CH2Cl2 4: 82 percent / PdCl2 (dppf); dppf; KOAc / dioxane View Scheme
参考文献
Matasi, Julius J.; Caldwell, John P.; Zhang, Hongtao; Fawzi, Ahmad; Higgins, Guy A.; Cohen-Williams, Mary E.; Varty, Geoffrey B.; Tulshian, Deen B.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 16 p. 3675 - 3678
反应条件
2,6-dimethylpyridine in dichloromethane
T=0°C; 2 h;
参考文献
Takeda Pharmaceutical Company Limited
Patent: EP1911738 A1, 2008 ;
Location in patent: Page/Page column 37 ;
反应条件
in water; N,N-dimethyl-formamide
参考文献
Scanlan, Thomas S.; Shah, Nilesh
Patent: US2003/176478 A1, 2003 ;
US 20030176478 A1
反应条件
triethylamine in dichloromethane
T=20°C; 18 h; Inert atmosphere;
参考文献
Kapdi, Anant R.; Fairlamb, Ian J. S.
New Journal of Chemistry, 2013 , vol. 37, # 4 p. 961 - 964
反应条件
1: 83 percent / Pd(OAc)2; P(tBu)3; NaOtBu / toluene
2: 89 percent / tetrabutylammonium fluoride / tetrahydrofuran
3: 85 percent / Et3N / CH2Cl2
4: 40 percent / PdCl2 (dppf); dppf; KOAc / dioxane
View Scheme
参考文献
Matasi, Julius J.; Caldwell, John P.; Zhang, Hongtao; Fawzi, Ahmad; Higgins, Guy A.; Cohen-Williams, Mary E.; Varty, Geoffrey B.; Tulshian, Deen B.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 16 p. 3675 - 3678
