2-(甲基硫代)噻唑并[5,4-b]吡啶合成路线

参考文献

AMGEN INC.; Allen, Jennifer R.; Amegadzie, Albert; Andrews, Kristin L.; Brown, James; Chen, Jian J.; Chen, Ning; Harrington, Essa Hu; Liu, Qingyian; Nguyen, Thomas T.; Pickrell, Alexander J.; Qian, Wenyuan; Rumfelt, Shannon; Rzasa, Robert M.; Yuan, Chester Chenguang; Zhong, Wenge
Patent: US2013/225552 A1, 2013 ;
Location in patent: Paragraph 0655; 0656 ;

5470-18-82-氯-3-硝基吡啶

57135-10-12-(甲基硫代)噻唑并[5,4-b]吡啶

参考文献

Walczyski, Krzysztof; Zuiderveld, Obbe P.; Timmerman, Henk
European Journal of Medicinal Chemistry, 2005 , vol. 40, # 1 p. 15 - 23

38240-21-02-巯基-3-氨基吡啶

57135-10-12-(甲基硫代)噻唑并[5,4-b]吡啶

参考文献

Barlin; Ireland; Rowland
Australian Journal of Chemistry, 1984 , vol. 37, # 8 p. 1729 - 1737

39856-58-12-溴-3-氨基吡啶

57135-10-12-(甲基硫代)噻唑并[5,4-b]吡啶

参考文献

AMGEN INC.; Allen, Jennifer R.; Amegadzie, Albert; Andrews, Kristin L.; Brown, James; Chen, Jian J.; Chen, Ning; Harrington, Essa Hu; Liu, Qingyian; Nguyen, Thomas T.; Pickrell, Alexander J.; Qian, Wenyuan; Rumfelt, Shannon; Rzasa, Robert M.; Yuan, Chester Chenguang; Zhong, Wenge
Patent: US2013/225552 A1, 2013 ;

109-01-3N-甲基哌嗪+

57135-10-12-(甲基硫代)噻唑并[5,4-b]吡啶

67219-28-7

参考文献

Gayral; Bourdais; Lorre; et al.
European Journal of Medicinal Chemistry, 1978 , vol. 13, # 2 p. 171 - 175

57135-10-12-(甲基硫代)噻唑并[5,4-b]吡啶

57135-11-2

参考文献

Bednyagina,N.P. et al.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1975 , vol. 11, p. 811 - 813
Khimiya Geterotsiklicheskikh Soedinenii, 1975 , vol. 11, # 7 p. 925 - 927