3,4-二氢-2(1H)-吡啶酮合成路线 （共 11 条）
反应条件
sodium hydride in tetrahydrofuran T=20°C; 12 h;
参考文献
Salanski, Piotr; Young, Kwan Ko; Lee, Kee-In
Mendeleev Communications, 2006 , # 1 p. 46 - 48
反应条件
hydrogen; RhCl(PPh3)3; triphenylphosphine in tetrahydrofuran
T=80°C; P=62057.8 Torr; 40 h;
参考文献
Ojima, Iwao; Korda, Anna; Shay, William R.
Journal of Organic Chemistry, 1991 , vol. 56, # 6 p. 2024 - 2030
反应条件
hydrogen; bis(triphenylphosphine)carbonylrhodium(I) chloride in tetrahydrofuran
T=100°C; P=62057.8 Torr; 5 h;
参考文献
Ojima, Iwao; Korda, Anna; Shay, William R.
Journal of Organic Chemistry, 1991 , vol. 56, # 6 p. 2024 - 2030
反应条件
pyridine; pyridinium p-toluenesulfonate in toluene
T=110°C; 8 h; Inert atmosphere;
参考文献
Jana, Somnath; Rainier, Jon D.
Organic Letters, 2013 , vol. 15, # 17 p. 4426 - 4429
反应条件
hydrogen; RhCl(PPh3)3 in tetrahydrofuran
T=80°C; P=62057.8 Torr; 9 h; other catalysts; variation of conditions; other alkenamides; Product distributionMechanism;
参考文献
Ojima, Iwao; Korda, Anna; Shay, William R.
Journal of Organic Chemistry, 1991 , vol. 56, # 6 p. 2024 - 2030
反应条件
[Rh(bis(N-methylimidazol-2-yl)methane)(CO)2](1+)[BPh4](1-) in THF-d8 (tetrahydrofuran-d8)
T=60°C; 24 h;
参考文献
Burling, Suzanne; Field, Leslie D.; Li, Hsiu L.; Messerle, Barbara A.; Shasha, Adelle
Australian Journal of Chemistry, 2004 , vol. 57, # 7 p. 677 - 680
反应条件
T=600°C; P=0.01 Torr; 1 h; Flash photolysis;
参考文献
Chou, Chin-Hsing; Chu, Li-Tse; Chen, I-Ying; Wu, Bo-Jian
Heterocycles, 2008 , vol. 75, # 3 p. 577 - 582
反应条件
1.1: sodium tetrahydroborate / 2 h / 0 °C / |Inert atmosphere
1.2: 0.75 h / 0 °C / pH 3 / |Inert atmosphere
2.1: pyridine; pyridinium p-toluenesulfonate / toluene / 8 h / 110 °C / |Inert atmosphere
View Scheme
参考文献
Jana, Somnath; Rainier, Jon D.
Organic Letters, 2013 , vol. 15, # 17 p. 4426 - 4429
反应条件
1.1: 1-cyclohexyl-3-(2-morpholinoethyl)carbodiimide tosylate / CHCl3 / 18 h / 20 °C
1.2: 47 percent / NH3 / CHCl3 / 18 h / 20 °C
2.1: 11 percent / [Rh(bis(N-methylimidazol-2-yl)methane)(CO)2](1+)[BPh4](1-) / tetrahydrofuran-d8 / 24 h / 60 °C
View Scheme
参考文献
Burling, Suzanne; Field, Leslie D.; Li, Hsiu L.; Messerle, Barbara A.; Shasha, Adelle
Australian Journal of Chemistry, 2004 , vol. 57, # 7 p. 677 - 680
反应条件
toluene-4-sulfonic acid
Inert atmosphere;
参考文献
Vicente-Garcia, Esther; Catti, Federica; Ramon, Rosario; Lavilla, Rodolfo
Organic Letters, 2010 , vol. 12, # 4 p. 860 - 863
