N-ethyl-N,N-diisopropylamine; trichlorophosphate in 1,2-dichloro-ethane Heating / reflux;
参考文献
ARRAY BIOPHARMA INC.; MITCHELL, Ian S.; BLAKE, James F.; XU, Rui; KALLAN, Nicholas C.; XIAO, Dengming; SPENCER, Keith Lee; BENCSIK, Josef R.
Patent: WO2008/6039 A1, 2008 ;
Location in patent: Page/Page column 79 ;
WO 2008/006039 A1
1: carboxamidine hydrochloride With sodium ethanolate in ethanol
T=20°C; 1 h;
2: Methyl tetrahydro-4-oxo-3-thiophenecarboxylate in ethanol
T=20°C; Heating / reflux;
参考文献
ARRAY BIOPHARMA INC.; MITCHELL, Ian S.; BLAKE, James F.; XU, Rui; KALLAN, Nicholas C.; XIAO, Dengming; SPENCER, Keith Lee; BENCSIK, Josef R.
Patent: WO2008/6039 A1, 2008 ;
Location in patent: Page/Page column 78-79 ;
WO 2008/006039 A1
