2-(3,4-二甲氧基苯基)-4,4-二甲基-4,5-二氢-1,3-噁唑合成路线 （共 4 条）
反应条件
1: SOCl2
2: 2.) SOCl2 / 1.) CH2Cl2, r.t., 2.5 h, 2.) C6H6, r.t., overnight
View Scheme
参考文献
Hattori, Tetsutaro; Takeda, Ayanobu; Suzuki, Kenji; Koike, Nobuyuki; Koshiishi, Eiji; Miyano, Sotaro
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 22 p. 3661 - 3671
反应条件
1: CH2Cl2 / Ambient temperature
2: SOCl2
View Scheme
参考文献
Nie, Jun-ying; Kirk, Kenneth L.
Journal of Fluorine Chemistry, 1995 , vol. 74, # 2 p. 297 - 302
反应条件
thionyl chloride
1.) CH2Cl2, r.t., 2.5 h, 2.) C6H6, r.t., overnight; Yield given. Multistep reaction;
参考文献
Hattori, Tetsutaro; Takeda, Ayanobu; Suzuki, Kenji; Koike, Nobuyuki; Koshiishi, Eiji; Miyano, Sotaro
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 22 p. 3661 - 3671
反应条件
n-butyllithium
1.) n-hexane, THF, -45 deg C, 2 h, 2.) a) n-hexane, THF, -45 deg C, 1 h, b) RT, overnight; Yield given. Multistep reaction;
参考文献
Ogawa, Yoshimitsu; Hosaka, Kunio; Chin, Masao; Mitsuhashi, Hiroshi
Heterocycles, 1991 , vol. 32, # 9 p. 1737 - 1744
