反应条件
1: (E)-3-(2-Bromomethyl-phenyl)-acryloyl chloride With N-ethyl-N,N-diisopropylamine; Wang resin in dichloromethane T=0 - 20°C; 2: 2-Methoxyphenyl-dihydroxyborane With tetrakis(triphenylphosphine) palladium(0); cesium fluoride in ethylene glycol dimethyl ether T=95°C; Suzuki coupling; 10 h; 3: With trifluoroacetic acid in dichloromethane T=20°C; 0.166667 h; Title compound not separated from byproducts;
参考文献
Juteau, Helene; Gareau, Yves; Labelle, Marc; Lamontagne, Sonia; Tremblay, Nathalie; Carriere, Marie-Claude; Sawyer, Nicole; Denis, Danielle; Metters, Kathleen M.
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 5 p. 747 - 749
