N-叔丁氧羰基-1,2-乙二胺合成路线 （共 68 条）
反应条件
ethylenediamine in tetrahydrofuran; water
反应条件
sodium hydrogencarbonate in water
反应条件
in dichloromethane T=20°C; 29 h; Inert atmosphere;
参考文献
Landi, Felicetta; Johansson, Conny M.; Campopiano, Dominic J.; Hulme, Alison N.
Organic and Biomolecular Chemistry, 2010 , vol. 8, # 1 p. 56 - 59
反应条件
in 1,4-dioxane T=20°C; 2 h; Inert atmosphere;
参考文献
EP2253621 A1, ;
Page/Page column 26 ;
反应条件
triethylamine in chloroform 4 h; Ambient temperature;
参考文献
Essien; Lai; Hwang
Journal of Medicinal Chemistry, 1988 , vol. 31, # 5 p. 898 - 901
反应条件
sodium hydroxide in tetrahydrofuran
反应条件
in N,N-dimethyl-formamide
参考文献
Hyrup, Birgitte; Egholm, Michael; Nielsen, Peter E.; Wittung, Pernilla; Norden, Bengt; Buchardf, Ole
Journal of the American Chemical Society, 1994 , vol. 116, # 18 p. 7964 - 7970
反应条件
1: 1.) diethyl azodicarboxylate (DEAD), triphenylphosphine, 2.) HN3 / 1.) THF, 0 deg C, 5 min, 2.) toluene, room temperature, 18 h 2: 50 mg / hydrazine monohydrate / Raney nickel / ethanol / 3 h / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 32, # 2 p. 391 - 396
反应条件
in dichloromethane; ethyl acetate
参考文献
US5011849 A1, ;
US 5011849 A
反应条件
in dichloromethane T=0 - 20°C; 24 h; Inert atmosphere;
参考文献
Cal, Pedro M.S.D.; Frade, Raquel F.M.; Chudasama, Vijay; Cordeiro, Carlos; Caddick, Stephen; Gois, Pedro M.P.
Chemical Communications, 2014 , vol. 50, # 40 p. 5261 - 5263
